Abby Stahl

Commercial Translation Architect

Identifies and advances immunotherapy, transplant, and molecular biology translational research projects that promote healthy aging towards clinical and commercial impact

PhD Candidate

Department of Pathology
University of Pittsburgh School of Medicine
Studies innate immune cell signaling pathways in aging and disease

Education and Experience

Abby is a PhD candidate with training in cellular and molecular pathology, presently conducting research in the laboratory of Dr. Bryan Brown at the McGowan Institute for Regenerative Medicine. Abby’s research focuses on age-associated changes in metabolism and inflammation, and she is dedicated to furthering our understanding of the molecular mechanisms underlying the natural aging process. Through her research, Abby has earned experience in project management, collaboration with industry partners, and grant writing. Outside of the lab, Abby has been very involved in student leadership and advocacy, serving as president of the Biomedical Graduate Student Association and a member of the University Council on Graduate Studies. Abby also works with traditionally underrepresented students in STEM fields on fun, interactive lessons in bioengineering as an instructor and consultant for the Investing Now program and enjoys participating in community science outreach events.

Education

BS, Bioengineering, University of Pittsburgh, 2013

Research Experience

Graduate Research, Department of Pathology, University of Pittsburgh
Advisor: Bryan Brown, PhD
  • Identify phenotypical and functional changes in tissue-specific macrophage subsets during aging and modulating age-associated inflammation in the murine liver
Advisor: Johnny Huard, PhD
  • Design and implement a controlled release system for therapeutic delivery of hepatocyte growth factor to dystrophic muscle
Advisor: Lisa Butterfield, PhD
  • Evaluate the role of tumor derived alpha-fetoprotein on natural killer cell activation towards the development of novel cancer immunotherapies
Undergraduate Research, University of Pittsburgh
Advisor: Stephen Badylak, MD, PhD, DVM
  • Assessed macrophage polarization in response to decellularized porcine central nervous system scaffolds for tissue engineering applications
Advisor: Helena Kuivaniemi, MD, PhD, FAHA
  • Identified novel pathways in human abdominal aortic aneurysms, focused on activation of the natural killer cytotoxicity pathway

    Commercial Translation Experience

    • Successfully managed and conducted industry-sponsored research collaborations
    • Co-inventor on two unique invention disclosures filed with the University of Pittsburgh
    • Hired as a consultant on a Small Business Innovation Research (SBIR) grant for a local start-up company, developing SOPs for manufacturing, verification, and validation processes for a 510(k) device
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    Megan Breski, MS

    Clinical and Translational Science Institute Program Manager